Malignant tumors of the small intestine

Malignant tumors of the small intestineAre rare. Carcinoid is localized most frequently in the terminal ileum, is small in size, develops slowly. In the absence of secretion of serotonin clinical symptoms expressed little (diarrhea, weight loss). With increasing tumor gradually appear abdominal pain and symptoms of partial intestinal obstruction. The time from onset of symptoms before the diagnosis can be several years. Carcinoid syndrome, in addition to diarrhea, manifested by redness of the face and torso, a high content in urine 5-treated acid. The frequency of occurrence of carcinoid syndrome is 10-30%. Metastases of malignant carcinoid occur in the abdominal cavity, regional lymph nodes and liver. Sometimes metastases appear in many years. The main method of treatment is surgical. Five-year survival after radical surgery is 90%, 10-year - 75%. In the presence of metastases in the abdomen and lymph nodes, the 5-year survival rate was 57%, with metastases in the liver - 31 %. Chemotherapy can be effective (steptozotocin - 500 mg/m2/1 to 5 days in combination with 5-fluorouracil - 325 mg/m2/1-5th days). Adenocarcinoma localized more frequently in the duodenum and jejunum. It is intestinal bleeding, pain, weight loss, rarely occurring diarrhea, fever. Surgical treatment. Leiomyosarcoma can reach large sizes, is localized in the duodenum and jejunum. Manifests with pain and intestinal bleeding. Radical surgery heals 40% of patients. The differential diagnosis of tumors of the small intestine should be mindful of the possibility of development of lymphosarcoma and inflammatory diseases. Comments on this article yet. Be the first one! Write a comment.

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